AGPR54-Activating Mutation in a Patient with Central Precocious Puberty
نویسندگان
چکیده
منابع مشابه
Serum vitamin D levels in girls with central precocious puberty
Precocious puberty can cause several adverse effects on final growth and social behavior in girls. Recently studies showed that low serum vitamin D levels might be associated with precocious puberty. The aim of this research was to investigate the association between serum vitamin D levels and central precocious puberty in girls. Girls with central precocious puberty under the age of 8 we...
متن کاملWhether all patients with Central precocious puberty should be treated?
Extended Abstract Precocious puberty is the appearance of secondary sexual characteristics before 8 years old in girls and 9 years old in boys. Precocious puberty is divided into 3 groups of central, peripheral and normal variants. Central precocious puberty is accompanied by activation of hypothalamic-pituitary-gonadal axis which causes increase in secretion of GnRH, and in turn increase i...
متن کامل[Central precocious puberty].
Central precocious puberty, defined as the onset of puberty before the age 8 years in girls and 9 years in boys, results from a premature activation of gonadotropin-releasing hormone neurons in the hypothalamus. This condition is characterised by early pubertal changes, acceleration of growth velocity, and rapid bone maturation that often result in reduced adult height. It may be either idiopat...
متن کاملCentral precocious puberty in a girl with Prader-Willi syndrome.
Prader-Willi syndrome (PWS) is characterized by infantile lethargy and hypotonia causing poor feeding and failure to thrive, childhood obesity, short stature, and hypogonadism. The complex phenotype is most probably caused by a hypothalamic dysfunction that is responsible for the hormonal dysfunction. The resulting hypogonadism in PWS causes incomplete, delayed, and sometimes disordered puberta...
متن کاملSerum bisphenol A levels in girls with central precocious puberty
Bisphenol A (BPA) is a chemical widely used to make polycarbonate plastics and epoxy resins lining food and beverage containers. A number of in vitro and in vivo studies have demonstrated that BPA has an estrogenic effect by binding to the nuclear estrogen receptor, and early BPA exposure could in induce early puberty. However, effects of human exposure to BPA on pubertal onset and the associat...
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ژورنال
عنوان ژورنال: New England Journal of Medicine
سال: 2008
ISSN: 0028-4793,1533-4406
DOI: 10.1056/nejmoa073443